FR 3187 then LA 1525 at Madrid
Manchester → Madrid → São Paulo
Timetable, Madrid time
22:25FR 3187 from Manchester at the gate
11:45LA 1525 to São Paulo leaves the gatealso CX 1825, BA 4224, AY 5633, EI 5889, PC 7968, QR 8063
13 h 20 apart on the timetable, overnight
LA 1525 leaves 13 h 20 after FR 3187 arrives on the timetable: more than half a day, so not a connection we count.