FR 3187 then LO 4763 at Madrid
Manchester → Madrid → Lisbon
Timetable, Madrid time
20:25FR 3187 from Manchester at the gate
18:00LO 4763 to Lisbon leaves the gate
21 h 35 apart on the timetable, overnight
LO 4763 leaves 21 h 35 after FR 3187 arrives on the timetable: more than half a day, so not a connection we count.