FR 4065 then FR 6410 at Madrid
Catania → Madrid → Sofia
Timetable, Madrid time
15:10FR 4065 from Catania at the gate
12:30FR 6410 to Sofia leaves the gate
21 h 20 apart on the timetable, overnight
FR 6410 leaves 21 h 20 after FR 4065 arrives on the timetable: more than half a day, so not a connection we count.