FR 5316 then AV 2498 at Madrid
Rome → Madrid → Lisbon
Timetable, Madrid time
23:40FR 5316 from Rome at the gate
21:10AV 2498 to Lisbon leaves the gatealso LO 4729, AD 7287, S4 8697
21 h 30 apart on the timetable, overnight
AV 2498 leaves 21 h 30 after FR 5316 arrives on the timetable: more than half a day, so not a connection we count.