FR 5316 then LH 1113 at Madrid
Rome → Madrid → Frankfurt am Main
Timetable, Madrid time
16:05FR 5316 from Rome at the gate
13:20LH 1113 to Frankfurt am Main leaves the gate
21 h 15 apart on the timetable, overnight
LH 1113 leaves 21 h 15 after FR 5316 arrives on the timetable: more than half a day, so not a connection we count.