FR 9601 then AV 6518 at Madrid
Rome → Madrid → Frankfurt am Main
Timetable, Madrid time
19:10FR 9601 from Rome at the gate
13:20AV 6518 to Frankfurt am Main leaves the gate
18 h 10 apart on the timetable, overnight
AV 6518 leaves 18 h 10 after FR 9601 arrives on the timetable: more than half a day, so not a connection we count.