IB 648 then U2 2708 at Madrid
Rome → Madrid → Bristol
Timetable, Madrid time
14:35IB 648 from Rome at the gate
10:20U2 2708 to Bristol leaves the gate
19 h 45 apart on the timetable, overnight
U2 2708 leaves 19 h 45 after IB 648 arrives on the timetable: more than half a day, so not a connection we count.