U2 2047 then AV 2506 at Madrid
Manchester → Madrid → Lisbon
Timetable, Madrid time
20:55U2 2047 from Manchester at the gate
18:00AV 2506 to Lisbon leaves the gatealso LO 4763, EK 4859, AD 7273, S4 8963
21 h 05 apart on the timetable, overnight
AV 2506 leaves 21 h 05 after U2 2047 arrives on the timetable: more than half a day, so not a connection we count.