U2 2047 then IB 721 at Madrid
Manchester → Madrid → London Heathrow
Timetable, Madrid time
20:35U2 2047 from Manchester at the gate
15:50IB 721 to London Heathrow leaves the gatealso LA 1701, VY 5176, DT 6160, QR 6906, BA 7068, AA 8652
19 h 15 apart on the timetable, overnight
IB 721 leaves 19 h 15 after U2 2047 arrives on the timetable: more than half a day, so not a connection we count.