U2 2305 then VY 5219 at Madrid
London Luton → Madrid → Lisbon
Timetable, Madrid time
09:35U2 2305 from London Luton at the gate
22:55VY 5219 to Lisbon leaves the gatealso AY 5631, QR 6935
13 h 20 apart on the timetable
VY 5219 leaves 13 h 20 after U2 2305 arrives on the timetable: more than half a day, so not a connection we count.