UX 1066 then FR 5301 at Madrid
Milan → Madrid → Luxembourg
Timetable, Madrid time
12:45UX 1066 from Milan at the gatealso ET 1422, EY 4371, AM 6850, AD 7892
07:15FR 5301 to Luxembourg leaves the gate
18 h 30 apart on the timetable, overnight
FR 5301 leaves 18 h 30 after UX 1066 arrives on the timetable: more than half a day, so not a connection we count.