UX 5468 then U2 2306 at Madrid
Seville → Madrid → London Luton
Timetable, Madrid time
15:30UX 5468 from Seville at the gate
10:35U2 2306 to London Luton leaves the gate
19 h 05 apart on the timetable, overnight
U2 2306 leaves 19 h 05 after UX 5468 arrives on the timetable: more than half a day, so not a connection we count.