VY 5340 then FR 2753 at Madrid
Napoli → Madrid → Milan
Timetable, Madrid time
08:45VY 5340 from Napoli at the gatealso AA 8561
22:10FR 2753 to Milan leaves the gate
13 h 25 apart on the timetable
FR 2753 leaves 13 h 25 after VY 5340 arrives on the timetable: more than half a day, so not a connection we count.