VY 5340 then FR 5301 at Madrid
Napoli → Madrid → Luxembourg
Timetable, Madrid time
08:45VY 5340 from Napoli at the gatealso AA 8561
07:15FR 5301 to Luxembourg leaves the gate
22 h 30 apart on the timetable, overnight
FR 5301 leaves 22 h 30 after VY 5340 arrives on the timetable: more than half a day, so not a connection we count.