W4 5373 then FR 5315 at Madrid
London Luton → Madrid → Rome
Timetable, Madrid time
01:10W4 5373 from London Luton at the gate
18:05FR 5315 to Rome leaves the gate
16 h 55 apart on the timetable
FR 5315 leaves 16 h 55 after W4 5373 arrives on the timetable: more than half a day, so not a connection we count.