W4 6313 then AV 2498 at Madrid
Milan → Madrid → Lisbon
Timetable, Madrid time
22:25W4 6313 from Milan at the gate
21:10AV 2498 to Lisbon leaves the gatealso LO 4729, AD 7287, S4 8697
22 h 45 apart on the timetable, overnight
AV 2498 leaves 22 h 45 after W4 6313 arrives on the timetable: more than half a day, so not a connection we count.