W4 7451 then FR 9674 at Madrid
Santiago de Compostela → Madrid → Rome
Timetable, Madrid time
13:00W4 7451 from Santiago de Compostela at the gate
10:25FR 9674 to Rome leaves the gate
21 h 25 apart on the timetable, overnight
FR 9674 leaves 21 h 25 after W4 7451 arrives on the timetable: more than half a day, so not a connection we count.