BY 2521 then U2 2201 at Manchester
Paphos → Manchester → Berlin
Timetable, Manchester time
01:55BY 2521 from Paphos at the gate
18:45U2 2201 to Berlin leaves the gate
16 h 50 apart on the timetable
U2 2201 leaves 16 h 50 after BY 2521 arrives on the timetable: more than half a day, so not a connection we count.