BY 2521 then U2 2231 at Manchester
Paphos → Manchester → Prague
Timetable, Manchester time
01:55BY 2521 from Paphos at the gate
17:25U2 2231 to Prague leaves the gate
15 h 30 apart on the timetable
U2 2231 leaves 15 h 30 after BY 2521 arrives on the timetable: more than half a day, so not a connection we count.