BY 2649 then U2 2133 at Manchester
Paphos → Manchester → Catania
Timetable, Manchester time
18:10BY 2649 from Paphos at the gate
07:30U2 2133 to Catania leaves the gate
13 h 20 apart on the timetable, overnight
U2 2133 leaves 13 h 20 after BY 2649 arrives on the timetable: more than half a day, so not a connection we count.