BY 2649 then U2 2273 at Manchester
Paphos → Manchester → Valletta
Timetable, Manchester time
18:10BY 2649 from Paphos at the gate
14:15U2 2273 to Valletta leaves the gate
20 h 05 apart on the timetable, overnight
U2 2273 leaves 20 h 05 after BY 2649 arrives on the timetable: more than half a day, so not a connection we count.