FR 1592 then FR 6818 at Manchester
Cologne → Manchester → Milan
Timetable, Manchester time
14:10FR 1592 from Cologne at the gate
05:55FR 6818 to Milan leaves the gate
15 h 45 apart on the timetable, overnight
FR 6818 leaves 15 h 45 after FR 1592 arrives on the timetable: more than half a day, so not a connection we count.