FR 301 then U2 2201 at Manchester
Lisbon → Manchester → Berlin
Timetable, Manchester time
00:15FR 301 from Lisbon at the gate
18:15U2 2201 to Berlin leaves the gate
18 h apart on the timetable
U2 2201 leaves 18 h after FR 301 arrives on the timetable: more than half a day, so not a connection we count.