FR 3953 then FR 892 at Manchester
Lisbon → Manchester → Knock
Timetable, Manchester time
12:15FR 3953 from Lisbon at the gate
10:15FR 892 to Knock leaves the gate
22 h apart on the timetable, overnight
FR 892 leaves 22 h after FR 3953 arrives on the timetable: more than half a day, so not a connection we count.