FR 5270 then U2 2123 at Manchester
Barcelona → Manchester → Rome
Timetable, Manchester time
14:20FR 5270 from Barcelona at the gate
12:15U2 2123 to Rome leaves the gate
21 h 55 apart on the timetable, overnight
U2 2123 leaves 21 h 55 after FR 5270 arrives on the timetable: more than half a day, so not a connection we count.