FR 6573 then U2 2201 at Manchester
Cologne → Manchester → Berlin
Timetable, Manchester time
01:00FR 6573 from Cologne at the gate
18:15U2 2201 to Berlin leaves the gate
17 h 15 apart on the timetable
U2 2201 leaves 17 h 15 after FR 6573 arrives on the timetable: more than half a day, so not a connection we count.