FR 6817 then U2 2169 at Manchester
Milan → Manchester → Amsterdam
Timetable, Manchester time
21:00FR 6817 from Milan at the gate
13:15U2 2169 to Amsterdam leaves the gate
16 h 15 apart on the timetable, overnight
U2 2169 leaves 16 h 15 after FR 6817 arrives on the timetable: more than half a day, so not a connection we count.