LS 906 then U2 2273 at Manchester
Heraklion → Manchester → Valletta
Timetable, Manchester time
01:50LS 906 from Heraklion at the gate
14:35U2 2273 to Valletta leaves the gate
12 h 45 apart on the timetable
U2 2273 leaves 12 h 45 after LS 906 arrives on the timetable: more than half a day, so not a connection we count.