U2 2078 then U2 2231 at Manchester
Kos → Manchester → Prague
Timetable, Manchester time
01:30U2 2078 from Kos at the gate
17:25U2 2231 to Prague leaves the gate
15 h 55 apart on the timetable
U2 2231 leaves 15 h 55 after U2 2078 arrives on the timetable: more than half a day, so not a connection we count.