U2 2100 then U2 2273 at Manchester
Paphos → Manchester → Valletta
Timetable, Manchester time
00:45U2 2100 from Paphos at the gate
15:50U2 2273 to Valletta leaves the gate
15 h 05 apart on the timetable
U2 2273 leaves 15 h 05 after U2 2100 arrives on the timetable: more than half a day, so not a connection we count.