U2 2122 then FR 641 at Manchester
Venezia → Manchester → Valencia
Timetable, Manchester time
13:35U2 2122 from Venezia at the gate
09:05FR 641 to Valencia leaves the gate
19 h 30 apart on the timetable, overnight
FR 641 leaves 19 h 30 after U2 2122 arrives on the timetable: more than half a day, so not a connection we count.