U2 2124 then LM 698 at Manchester
Rome → Manchester → Castletown
Timetable, Manchester time
18:30U2 2124 from Rome at the gate
16:45LM 698 to Castletown leaves the gate
22 h 15 apart on the timetable, overnight
LM 698 leaves 22 h 15 after U2 2124 arrives on the timetable: more than half a day, so not a connection we count.