U2 2124 then LS 929 at Manchester
Rome → Manchester → Reus
Timetable, Manchester time
22:50U2 2124 from Rome at the gate
15:35LS 929 to Reus leaves the gate
16 h 45 apart on the timetable, overnight
LS 929 leaves 16 h 45 after U2 2124 arrives on the timetable: more than half a day, so not a connection we count.