U2 2124 then U2 2263 at Manchester
Rome → Manchester → Krakow
Timetable, Manchester time
18:30U2 2124 from Rome at the gate
16:40U2 2263 to Krakow leaves the gate
22 h 10 apart on the timetable, overnight
U2 2263 leaves 22 h 10 after U2 2124 arrives on the timetable: more than half a day, so not a connection we count.