U2 2130 then BY 2676 at Manchester
Pisa → Manchester → Tenerife South
Timetable, Manchester time
12:15U2 2130 from Pisa at the gate
09:10BY 2676 to Tenerife South leaves the gate
20 h 55 apart on the timetable, overnight
BY 2676 leaves 20 h 55 after U2 2130 arrives on the timetable: more than half a day, so not a connection we count.