U2 2130 then FR 555 at Manchester
Pisa → Manchester → Dublin
Timetable, Manchester time
12:15U2 2130 from Pisa at the gate
06:00FR 555 to Dublin leaves the gate
17 h 45 apart on the timetable, overnight
FR 555 leaves 17 h 45 after U2 2130 arrives on the timetable: more than half a day, so not a connection we count.