U2 2130 then FR 561 at Manchester
Pisa → Manchester → Dublin
Timetable, Manchester time
12:15U2 2130 from Pisa at the gate
08:10FR 561 to Dublin leaves the gate
19 h 55 apart on the timetable, overnight
FR 561 leaves 19 h 55 after U2 2130 arrives on the timetable: more than half a day, so not a connection we count.