U2 2152 then FR 6818 at Manchester
Valletta → Manchester → Milan
Timetable, Manchester time
14:35U2 2152 from Valletta at the gate
05:55FR 6818 to Milan leaves the gate
15 h 20 apart on the timetable, overnight
FR 6818 leaves 15 h 20 after U2 2152 arrives on the timetable: more than half a day, so not a connection we count.