U2 2162 then FR 6818 at Manchester
Amsterdam → Manchester → Milan
Timetable, Manchester time
10:25U2 2162 from Amsterdam at the gate
05:55FR 6818 to Milan leaves the gate
19 h 30 apart on the timetable, overnight
FR 6818 leaves 19 h 30 after U2 2162 arrives on the timetable: more than half a day, so not a connection we count.