U2 2162 then FR 6842 at Manchester
Amsterdam → Manchester → Prague
Timetable, Manchester time
10:25U2 2162 from Amsterdam at the gate
08:25FR 6842 to Prague leaves the gate
22 h apart on the timetable, overnight
FR 6842 leaves 22 h after U2 2162 arrives on the timetable: more than half a day, so not a connection we count.