U2 2194 then BQ 2322 at Manchester
Zurich → Manchester → Rome
Timetable, Manchester time
21:55U2 2194 from Zurich at the gate
16:00BQ 2322 to Rome leaves the gate
18 h 05 apart on the timetable, overnight
BQ 2322 leaves 18 h 05 after U2 2194 arrives on the timetable: more than half a day, so not a connection we count.