U2 2194 then TK 1992 at Manchester
Zurich → Manchester → Istanbul
Timetable, Manchester time
21:55U2 2194 from Zurich at the gate
14:00TK 1992 to Istanbul leaves the gate
16 h 05 apart on the timetable, overnight
TK 1992 leaves 16 h 05 after U2 2194 arrives on the timetable: more than half a day, so not a connection we count.