U2 2202 then U2 2273 at Manchester
Berlin → Manchester → Valletta
Timetable, Manchester time
22:55U2 2202 from Berlin at the gate
15:50U2 2273 to Valletta leaves the gate
16 h 55 apart on the timetable, overnight
U2 2273 leaves 16 h 55 after U2 2202 arrives on the timetable: more than half a day, so not a connection we count.