U2 2210 then FR 5209 at Manchester
Lisbon → Manchester → Valletta
Timetable, Manchester time
15:00U2 2210 from Lisbon at the gate
10:55FR 5209 to Valletta leaves the gate
19 h 55 apart on the timetable, overnight
FR 5209 leaves 19 h 55 after U2 2210 arrives on the timetable: more than half a day, so not a connection we count.