U2 2230 then FR 4027 at Manchester
Prague → Manchester → Alicante
Timetable, Manchester time
12:30U2 2230 from Prague at the gate
10:35FR 4027 to Alicante leaves the gate
22 h 05 apart on the timetable, overnight
FR 4027 leaves 22 h 05 after U2 2230 arrives on the timetable: more than half a day, so not a connection we count.