U2 2230 then FR 4370 at Manchester
Prague → Manchester → Seville
Timetable, Manchester time
12:15U2 2230 from Prague at the gate
10:30FR 4370 to Seville leaves the gate
22 h 15 apart on the timetable, overnight
FR 4370 leaves 22 h 15 after U2 2230 arrives on the timetable: more than half a day, so not a connection we count.