U2 2230 then LS 891 at Manchester
Prague → Manchester → Lanzarote
Timetable, Manchester time
12:30U2 2230 from Prague at the gate
10:20LS 891 to Lanzarote leaves the gate
21 h 50 apart on the timetable, overnight
LS 891 leaves 21 h 50 after U2 2230 arrives on the timetable: more than half a day, so not a connection we count.