U2 2232 then LS 881 at Manchester
Prague → Manchester → Alicante
Timetable, Manchester time
22:35U2 2232 from Prague at the gate
14:50LS 881 to Alicante leaves the gate
16 h 15 apart on the timetable, overnight
LS 881 leaves 16 h 15 after U2 2232 arrives on the timetable: more than half a day, so not a connection we count.