U2 2280 then U2 2151 at Manchester
Paphos → Manchester → Valletta
Timetable, Manchester time
17:45U2 2280 from Paphos at the gate
06:45U2 2151 to Valletta leaves the gate
13 h apart on the timetable, overnight
U2 2151 leaves 13 h after U2 2280 arrives on the timetable: more than half a day, so not a connection we count.