U2 2280 then U2 2201 at Manchester
Paphos → Manchester → Berlin
Timetable, Manchester time
17:45U2 2280 from Paphos at the gate
12:55U2 2201 to Berlin leaves the gate
19 h 10 apart on the timetable, overnight
U2 2201 leaves 19 h 10 after U2 2280 arrives on the timetable: more than half a day, so not a connection we count.